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miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway

Osteoarthritis (OA) is a common degenerative disease in middle-aged and elderly people. Our previous study has proved that microRNA-7 (miR-7) exacerbated the OA process. This study was aimed to explore the downstream genes and mechanism regulated by miR-7 to affect OA. Multiple EGF-like-domains 9 (M...

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Detalles Bibliográficos
Autores principales: Jiang, Lifeng, Zhou, Xindie, Xu, Kai, Hu, Pengfei, Bao, Jiapeng, Li, Jin, Zhu, Junfeng, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806962/
https://www.ncbi.nlm.nih.gov/pubmed/34629037
http://dx.doi.org/10.1080/21655979.2021.1988362