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miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway
Osteoarthritis (OA) is a common degenerative disease in middle-aged and elderly people. Our previous study has proved that microRNA-7 (miR-7) exacerbated the OA process. This study was aimed to explore the downstream genes and mechanism regulated by miR-7 to affect OA. Multiple EGF-like-domains 9 (M...
Autores principales: | Jiang, Lifeng, Zhou, Xindie, Xu, Kai, Hu, Pengfei, Bao, Jiapeng, Li, Jin, Zhu, Junfeng, Wu, Lidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806962/ https://www.ncbi.nlm.nih.gov/pubmed/34629037 http://dx.doi.org/10.1080/21655979.2021.1988362 |
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