Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma

Hepatocellular carcinomas (HCCs) usually arise from chronic liver disease (CLD). Precancerous cells in chronically inflamed environments may be ‘epigenetically primed’, sensitising them to oncogenic transformation. We investigated whether epigenetic priming in CLD may affect HCC outcomes by influenc...

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Detalles Bibliográficos
Autores principales: Gallon, John, Coto‐Llerena, Mairene, Ercan, Caner, Bianco, Gaia, Paradiso, Viola, Nuciforo, Sandro, Taha‐Melitz, Stephanie, Meier, Marie‐Anne, Boldanova, Tujana, Pérez‐del‐Pulgar, Sofía, Rodríguez‐Tajes, Sergio, von Flüe, Markus, Soysal, Savas D., Kollmar, Otto, Llovet, Josep M., Villanueva, Augusto, Terracciano, Luigi M., Heim, Markus H., Ng, Charlotte K. Y., Piscuoglio, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807355/
https://www.ncbi.nlm.nih.gov/pubmed/34863035
http://dx.doi.org/10.1002/1878-0261.13154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807355/
https://www.ncbi.nlm.nih.gov/pubmed/34863035
http://dx.doi.org/10.1002/1878-0261.13154

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