Cargando…
Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma
Hepatocellular carcinomas (HCCs) usually arise from chronic liver disease (CLD). Precancerous cells in chronically inflamed environments may be ‘epigenetically primed’, sensitising them to oncogenic transformation. We investigated whether epigenetic priming in CLD may affect HCC outcomes by influenc...
Autores principales: | Gallon, John, Coto‐Llerena, Mairene, Ercan, Caner, Bianco, Gaia, Paradiso, Viola, Nuciforo, Sandro, Taha‐Melitz, Stephanie, Meier, Marie‐Anne, Boldanova, Tujana, Pérez‐del‐Pulgar, Sofía, Rodríguez‐Tajes, Sergio, von Flüe, Markus, Soysal, Savas D., Kollmar, Otto, Llovet, Josep M., Villanueva, Augusto, Terracciano, Luigi M., Heim, Markus H., Ng, Charlotte K. Y., Piscuoglio, Salvatore |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807355/ https://www.ncbi.nlm.nih.gov/pubmed/34863035 http://dx.doi.org/10.1002/1878-0261.13154 |
Ejemplares similares
-
Patient-derived tumor organoids for personalized medicine in a patient with rare hepatocellular carcinoma with neuroendocrine differentiation: a case report
por: Meier, Marie-Anne, et al.
Publicado: (2022) -
Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report
por: Ercan, Caner, et al.
Publicado: (2022) -
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo‐Independent Regulation of Heat Shock Protein 70 Family Members
por: Coto‐Llerena, Mairene, et al.
Publicado: (2021) -
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis
por: Taha-Mehlitz, Stephanie, et al.
Publicado: (2021) -
High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes
por: Coto-Llerena, Mairene, et al.
Publicado: (2020)