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Epigenetic readers and lung cancer: the rs2427964C>T variant of the bromodomain and extraterminal domain gene BRD3 is associated with poorer survival outcome in NSCLC

Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that regulate gene expression. We investigated whether variants in BET genes are associated with survival outcomes for lung cancer. To do this, the associations between 77 variants in BET family genes and survival outcomes we...

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Detalles Bibliográficos
Autores principales: Lee, Jang Hyuck, Yoo, Seung Soo, Hong, Mi Jeong, Choi, Jin Eun, Kang, Hyo‐Gyoung, Do, Sook Kyung, Lee, Won Kee, Choi, Sun Ha, Lee, Yong Hoon, Seo, Hyewon, Lee, Jaehee, Lee, Shin Yup, Cha, Seung Ick, Kim, Chang Ho, Lee, Eung Bae, Cho, Sukki, Jheon, Sanghoon, Park, Jae Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807359/
https://www.ncbi.nlm.nih.gov/pubmed/34605158
http://dx.doi.org/10.1002/1878-0261.13109