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Computational characterization of domain‐segregated 3D chromatin structure and segmented DNA methylation status in carcinogenesis

The high‐order chromatin structure, together with DNA methylation and other epigenetic marks, plays a vital role in gene regulation and displays abnormal status in cancer cells. Theoretical analyses are expected to provide a more unified understanding of the multi‐omics data on the large variety of...

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Detalles Bibliográficos
Autores principales: Xue, Yue, Yang, Ying, Tian, Hao, Quan, Hui, Liu, Sirui, Zhang, Ling, Yang, Lu, Zhu, Haichuan, Wu, Hong, Gao, Yi Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807360/
https://www.ncbi.nlm.nih.gov/pubmed/34708506
http://dx.doi.org/10.1002/1878-0261.13127