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Computational characterization of domain‐segregated 3D chromatin structure and segmented DNA methylation status in carcinogenesis
The high‐order chromatin structure, together with DNA methylation and other epigenetic marks, plays a vital role in gene regulation and displays abnormal status in cancer cells. Theoretical analyses are expected to provide a more unified understanding of the multi‐omics data on the large variety of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807360/ https://www.ncbi.nlm.nih.gov/pubmed/34708506 http://dx.doi.org/10.1002/1878-0261.13127 |