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Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease

We sought to determine the relationship between age-related clonal hematopoiesis (CH) and chronic kidney disease (CKD). CH, defined as mosaic chromosome abnormalities (mCA) and/or driver mutations was identified in 5449 (2.9%) eligible UK Biobank participants (n = 190,487 median age = 58 years). CH...

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Detalles Bibliográficos
Autores principales: Dawoud, Ahmed A. Z., Gilbert, Rodney D., Tapper, William J., Cross, Nicholas C. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807385/
https://www.ncbi.nlm.nih.gov/pubmed/34413458
http://dx.doi.org/10.1038/s41375-021-01382-3