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Clonal myelopoiesis promotes adverse outcomes in chronic kidney disease
We sought to determine the relationship between age-related clonal hematopoiesis (CH) and chronic kidney disease (CKD). CH, defined as mosaic chromosome abnormalities (mCA) and/or driver mutations was identified in 5449 (2.9%) eligible UK Biobank participants (n = 190,487 median age = 58 years). CH...
Autores principales: | Dawoud, Ahmed A. Z., Gilbert, Rodney D., Tapper, William J., Cross, Nicholas C. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807385/ https://www.ncbi.nlm.nih.gov/pubmed/34413458 http://dx.doi.org/10.1038/s41375-021-01382-3 |
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