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Indeterminate and oncogenic potential: CHIP vs CHOP mutations in AML with NPM1 alteration
In AML patients, recurrent mutations were shown to persist in remission, however, only some have a prognostic value and persistent mutations might therefore reflect a re-established premalignant state or truly active disease causing relapse. We aimed to dissect the nature of co-mutations in NPM1 mut...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807394/ https://www.ncbi.nlm.nih.gov/pubmed/34376804 http://dx.doi.org/10.1038/s41375-021-01368-1 |