Indeterminate and oncogenic potential: CHIP vs CHOP mutations in AML with NPM1 alteration

In AML patients, recurrent mutations were shown to persist in remission, however, only some have a prognostic value and persistent mutations might therefore reflect a re-established premalignant state or truly active disease causing relapse. We aimed to dissect the nature of co-mutations in NPM1 mut...

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Detalles Bibliográficos
Autores principales: Cappelli, Luca Vincenzo, Meggendorfer, Manja, Baer, Constance, Nadarajah, Niroshan, Hutter, Stephan, Jeromin, Sabine, Dicker, Frank, Kern, Wolfgang, Haferlach, Torsten, Haferlach, Claudia, Höllein, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807394/
https://www.ncbi.nlm.nih.gov/pubmed/34376804
http://dx.doi.org/10.1038/s41375-021-01368-1

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