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K‐29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis

Extracellular vesicles (EVs) are important mediators of intercellular communication. However, EV biogenesis remains poorly understood. We previously defined a role for Arrdc4 (Arrestin domain containing protein 4), an adaptor for Nedd4 family ubiquitin ligases, in the biogenesis of EVs. Here we repo...

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Detalles Bibliográficos
Autores principales: Farooq, Ammara Usman, Gembus, Kelly, Sandow, Jarrod J., Webb, Andrew, Mathivanan, Suresh, Manning, Jantina A., Shah, Sonia S., Foot, Natalie J., Kumar, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807422/
https://www.ncbi.nlm.nih.gov/pubmed/35106941
http://dx.doi.org/10.1002/jev2.12188