B1 siRNA Increases de novo DNA Methylation of B1 Elements and Promotes Wound Healing in Diabetic Rats

Alu (B1 in rodents) hypomethylation, commonly found in diabetes mellitus patients, increases DNA damage and, consequently, delays the healing process. Alu siRNA increases Alu methylation, reduces DNA damage, and promotes cell proliferation. Aim: To explore whether B1 siRNA treatment restores B1 hypo...

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Detalles Bibliográficos
Autores principales: Yasom, Sakawdaurn, Khumsri, Wilunplus, Boonsongserm, Papatson, Kitkumthorn, Nakarin, Ruangvejvorachai, Preecha, Sooksamran, Apasee, Wanotayan, Rujira, Mutirangura, Apiwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807477/
https://www.ncbi.nlm.nih.gov/pubmed/35127718
http://dx.doi.org/10.3389/fcell.2021.802024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807477/
https://www.ncbi.nlm.nih.gov/pubmed/35127718
http://dx.doi.org/10.3389/fcell.2021.802024

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