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TLR7 Signaling Shapes and Maintains Antibody Diversity Upon Virus-Like Particle Immunization

Virus-like particles (VLPs) are used in different marketed vaccines and are able to induce potent antibody responses. The innate pattern recognition receptors TLR7/8 recognize single stranded (ss) RNA naturally packaged into some VLPs and have been shown to enhance the production of IgG antibodies u...

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Detalles Bibliográficos
Autores principales: Chang, Xinyue, Krenger, Pascal, Krueger, Caroline C., Zha, Lisha, Han, Jiami, Yermanos, Alexander, Roongta, Salony, Mohsen, Mona O., Oxenius, Annette, Vogel, Monique, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807482/
https://www.ncbi.nlm.nih.gov/pubmed/35126381
http://dx.doi.org/10.3389/fimmu.2021.827256