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Bone Mesenchymal Stem Cell-Derived sEV-Encapsulated Thermosensitive Hydrogels Accelerate Osteogenesis and Angiogenesis by Release of Exosomal miR-21

Angiogenesis has been recognized to play an essential role in remodeling new bone (osteogenesis). Small extracellular vesicles (sEVs), the endogenously secreted nanovesicles by cells, exhibit great potential in the regeneration of bone defects and the realization of cell-free therapy. Chitosan, a na...

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Detalles Bibliográficos
Autores principales: Wu, Di, Qin, Hao, Wang, Zixuan, Yu, Mingzhao, Liu, Zhe, Peng, Hao, Liang, Leilei, Zhang, Changqing, Wei, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807520/
https://www.ncbi.nlm.nih.gov/pubmed/35127680
http://dx.doi.org/10.3389/fbioe.2021.829136