The rat rotenone model reproduces the abnormal pattern of central catecholamine metabolism found in Parkinson's disease

Recent reports indicate that Parkinson's disease (PD) involves specific functional abnormalities in residual neurons – decreased vesicular sequestration of cytoplasmic catecholamines via the vesicular monoamine transporter (VMAT) and decreased aldehyde dehydrogenase (ALDH) activity. This double...

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Detalles Bibliográficos
Autores principales: Landau, Regev, Halperin, Reut, Sullivan, Patti, Zibly, Zion, Leibowitz, Avshalom, Goldstein, David S., Sharabi, Yehonatan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807569/
https://www.ncbi.nlm.nih.gov/pubmed/34842277
http://dx.doi.org/10.1242/dmm.049082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807569/
https://www.ncbi.nlm.nih.gov/pubmed/34842277
http://dx.doi.org/10.1242/dmm.049082

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