Ovarian toxicity of carboplatin and paclitaxel in mouse carriers of mutation in BRIP1 tumor suppressor gene

More than 10% of women diagnosed with breast cancer during reproductive age carry hereditary germline pathogenic variants in high-penetrance BRCA genes or in others genes involved in DNA repair mechanisms such as PALB2, BRIP or ATM. Anticancer treatments may have an additional negative impact on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Ntemou, E., Vidal, P. Diaz, Alexandri, C., Van den Steen, G., Lambertini, M., Demeestere, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807594/
https://www.ncbi.nlm.nih.gov/pubmed/35105904
http://dx.doi.org/10.1038/s41598-022-05357-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807594/
https://www.ncbi.nlm.nih.gov/pubmed/35105904
http://dx.doi.org/10.1038/s41598-022-05357-x

Ejemplares similares