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C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice

Increased levels of pro-inflammatory cytokines have been reported in postmortem brain samples and in the blood of depressed subjects. However, the inflammatory pathways that lead to depressive-like symptoms are not well understood. Using the learned helplessness (LH) model of depression, we examined...

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Detalles Bibliográficos
Autores principales: Madeshiya, Amit Kumar, Whitehead, Carl, Tripathi, Ashutosh, Pillai, Anilkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807734/
https://www.ncbi.nlm.nih.gov/pubmed/35105860
http://dx.doi.org/10.1038/s41398-022-01794-4