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Cardiac Gene Therapy With Relaxin Receptor 1 Overexpression Protects Against Acute Myocardial Infarction

Relaxin is a pleiotropic hormone shown to confer cardioprotection in several preclinical models of cardiac ischemia-reperfusion injury. In the present study, the effects of up-regulating relaxin family peptide receptor 1 (RXFP1) via adeno-associated virus serotype 9 (AAV9) vectors were investigated...

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Detalles Bibliográficos
Autores principales: Devarakonda, Teja, Mauro, Adolfo G., Cain, Chad, Das, Anindita, Salloum, Fadi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807852/
https://www.ncbi.nlm.nih.gov/pubmed/35128209
http://dx.doi.org/10.1016/j.jacbts.2021.10.012