Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting

Unlike constitutively secreted proteins, peptide hormones are stored in densely packed secretory granules, before regulated release upon stimulation. Secretory granules are formed at the TGN by self-aggregation of prohormones as functional amyloids. The nonapeptide hormone vasopressin, which forms a...

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Detalles Bibliográficos
Autores principales: Reck, Jennifer, Beuret, Nicole, Demirci, Erhan, Prescianotto-Baschong, Cristina, Spiess, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807871/
https://www.ncbi.nlm.nih.gov/pubmed/35086936
http://dx.doi.org/10.26508/lsa.202101279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807871/
https://www.ncbi.nlm.nih.gov/pubmed/35086936
http://dx.doi.org/10.26508/lsa.202101279

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