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Recruitment of Scc2/4 to double-strand breaks depends on γH2A and DNA end resection
Homologous recombination enables cells to overcome the threat of DNA double-strand breaks (DSBs), allowing for repair without the loss of genetic information. Central to the homologous recombination repair process is the de novo loading of cohesin around a DSB by its loader complex Scc2/4. Although...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807874/ https://www.ncbi.nlm.nih.gov/pubmed/35086935 http://dx.doi.org/10.26508/lsa.202101244 |