Nucleotide biosynthesis links glutathione metabolism to ferroptosis sensitivity

Nucleotide synthesis is a metabolically demanding process essential for DNA replication and other processes in the cell. Several anticancer drugs that inhibit nucleotide metabolism induce apoptosis. How inhibition of nucleotide metabolism impacts non-apoptotic cell death is less clear. Here, we repo...

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Detalles Bibliográficos
Autores principales: Tarangelo, Amy, Rodencal, Jason, Kim, Joon Tae, Magtanong, Leslie, Long, Jonathan Z, Dixon, Scott J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807879/
https://www.ncbi.nlm.nih.gov/pubmed/35074928
http://dx.doi.org/10.26508/lsa.202101157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807879/
https://www.ncbi.nlm.nih.gov/pubmed/35074928
http://dx.doi.org/10.26508/lsa.202101157

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