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Carboranes as unique pharmacophores in antitumor medicinal chemistry

Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of benzene. It features special physical and chemical properties, and thus has the potential to serve as a new type of pharmacophore for drug design and discovery. Based on the relative positions of two cage carbons, ico...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Du, Fukuan, Tang, Liyao, Xu, Jinrun, Zhao, Yueshui, Wu, Xu, Li, Mingxing, Shen, Jing, Wen, Qinglian, Cho, Chi Hin, Xiao, Zhangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807988/
https://www.ncbi.nlm.nih.gov/pubmed/35141397
http://dx.doi.org/10.1016/j.omto.2022.01.005