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Patients with MPNs and retinal drusen show signs of complement system dysregulation and a high degree of chronic low-grade inflammation

BACKGROUND: The hematopoietic stem cell disorders, myeloproliferative neoplasms (MPNs), are characterised by chronic low-grade inflammation (CLI). Recently, we showed that patients with MPNs have an increased prevalence of drusen and age-related macular degeneration (AMD), and drusen prevalence seem...

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Detalles Bibliográficos
Autores principales: Liisborg, Charlotte, Skov, Vibe, Kjær, Lasse, Hasselbalch, Hans Carl, Sørensen, Torben Lykke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808164/
https://www.ncbi.nlm.nih.gov/pubmed/35128362
http://dx.doi.org/10.1016/j.eclinm.2021.101248