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Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites

The malaria-causing parasite Plasmodium falciparum is responsible for over 200 million infections and 400,000 deaths per year. At multiple stages during its complex life cycle, P. falciparum expresses several essential proteins tethered to its surface by glycosylphosphatidylinositol (GPI) anchors, w...

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Detalles Bibliográficos
Autores principales: Frasse, Philip M., Miller, Justin J., Polino, Alexander J., Soleimani, Ebrahim, Zhu, Jian-She, Jakeman, David L., Jez, Joseph M., Goldberg, Daniel E., Odom John, Audrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808168/
https://www.ncbi.nlm.nih.gov/pubmed/34973333
http://dx.doi.org/10.1016/j.jbc.2021.101550