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Protocol for inducing inflammation and acute myelin degeneration in larval zebrafish

This protocol details the induction of inflammation and acute myelin degeneration in larval zebrafish with a duration of <10 days. We describe the use of this model to screen the effects of candidate compounds on inflammation, followed by RNA isolation, and qPCR-based quantification of gene expre...

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Detalles Bibliográficos
Autores principales: Jaronen, Merja, Wheeler, Michael A., Quintana, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808285/
https://www.ncbi.nlm.nih.gov/pubmed/35128477
http://dx.doi.org/10.1016/j.xpro.2022.101134