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A Novel Humanized Anti-Interleukin-6 Antibody HZ0408b With Anti-Rheumatoid Arthritis Therapeutic Potential

Interleukin-6 (IL-6), a pleiotropic cytokine that regulates immune responses and inflammatory reactions, plays a pivotal role in the development of rheumatoid arthritis (RA). Blockade of IL-6 signaling with the monoclonal antibody (mAb) represents an important advancement in RA treatment. Although t...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolei, Li, Li, Wang, Qian, Jiang, Fengchao, Zhang, Pei, Guo, Fei, Liu, Hongjun, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808405/
https://www.ncbi.nlm.nih.gov/pubmed/35126375
http://dx.doi.org/10.3389/fimmu.2021.816646