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A Novel Humanized Anti-Interleukin-6 Antibody HZ0408b With Anti-Rheumatoid Arthritis Therapeutic Potential
Interleukin-6 (IL-6), a pleiotropic cytokine that regulates immune responses and inflammatory reactions, plays a pivotal role in the development of rheumatoid arthritis (RA). Blockade of IL-6 signaling with the monoclonal antibody (mAb) represents an important advancement in RA treatment. Although t...
Autores principales: | Liu, Xiaolei, Li, Li, Wang, Qian, Jiang, Fengchao, Zhang, Pei, Guo, Fei, Liu, Hongjun, Huang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808405/ https://www.ncbi.nlm.nih.gov/pubmed/35126375 http://dx.doi.org/10.3389/fimmu.2021.816646 |
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