New Molecular and Organelle Alterations Linked to Down Syndrome Heart Disease

Down syndrome (DS) is a genetic disorder caused by a trisomy of the human chromosome 21 (Hsa21). Overexpression of Hsa21 genes that encode proteins and non-coding RNAs (ncRNAs) can disrupt several cellular functions and biological processes, especially in the heart. Congenital heart defects (CHDs) a...

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Detalles Bibliográficos
Autores principales: Venegas-Zamora, Leslye, Bravo-Acuña, Francisco, Sigcho, Francisco, Gomez, Wileidy, Bustamante-Salazar, José, Pedrozo, Zully, Parra, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808411/
https://www.ncbi.nlm.nih.gov/pubmed/35126461
http://dx.doi.org/10.3389/fgene.2021.792231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808411/
https://www.ncbi.nlm.nih.gov/pubmed/35126461
http://dx.doi.org/10.3389/fgene.2021.792231

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