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Cell-type-specific epigenomic variations associated with BRCA1 mutation in pre-cancer human breast tissues
BRCA1 germline mutation carriers are predisposed to breast cancers. Epigenomic regulations have been known to strongly interact with genetic variations and potentially mediate biochemical cascades involved in tumorigenesis. Due to the cell-type specificity of epigenomic features, profiling of indivi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808540/ https://www.ncbi.nlm.nih.gov/pubmed/35118379 http://dx.doi.org/10.1093/nargab/lqac006 |