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Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model

BACKGROUND: Off-the-shelf major histocompatibility complex (MHC)-matched iPS cells (iPSC) can potentially initiate host immune responses because of the existence of numerous minor antigens. To suppress allo-immune responses, combination of immunosuppressants is usually used, but its efficacy to the...

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Detalles Bibliográficos
Autores principales: Kamatani, Tomoki, Otsuka, Ryo, Murata, Tomoki, Wada, Haruka, Takahashi, Takeshi, Mori, Akihiro, Murata, Soichiro, Taniguchi, Hideki, Seino, Ken-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809003/
https://www.ncbi.nlm.nih.gov/pubmed/35105370
http://dx.doi.org/10.1186/s41232-021-00190-7