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TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation

BACKGROUND: Systemic inflammation is a potent contributor to increased seizure susceptibility. However, information regarding the effects of systemic inflammation on cerebral vascular integrity that influence neuron excitability is scarce. Necroptosis is closely associated with inflammation in vario...

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Detalles Bibliográficos
Autores principales: Huang, Wan-Yu, Lai, Yen-Ling, Liu, Ko-Hung, Lin, Shankung, Chen, Hsuan-Ying, Liang, Chih-Hung, Wu, Hung-Ming, Hsu, Kuei-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809013/
https://www.ncbi.nlm.nih.gov/pubmed/35109859
http://dx.doi.org/10.1186/s12974-022-02406-0