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The Aβ1–42/Aβ1–40 ratio in CSF is more strongly associated to tau markers and clinical progression than Aβ1–42 alone

BACKGROUND: Cerebrospinal fluid (CSF) Aβ1–42 levels and the Aβ1–42/Aβ1–40 ratio are markers of amyloid pathology, but previous studies suggest that their levels might be influenced by additional pathophysiological processes. AIMS: To compare Aβ1–42 and the Aβ1–42/Aβ1–40 ratio in CSF in different neu...

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Detalles Bibliográficos
Autores principales: Delaby, Constance, Estellés, Teresa, Zhu, Nuole, Arranz, Javier, Barroeta, Isabel, Carmona-Iragui, María, Illán-Gala, Ignacio, Santos-Santos, Miguel Ángel, Altuna, Miren, Sala, Isabel, Sánchez-Saudinós, M. Belén, Videla, Laura, Valldeneu, Sílvia, Subirana, Andrea, Tondo, Mireia, Blanco-Vaca, Francisco, Lehmann, Sylvain, Belbin, Olivia, Blesa, Rafael, Fortea, Juan, Lleó, Alberto, Alcolea, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809019/
https://www.ncbi.nlm.nih.gov/pubmed/35105351
http://dx.doi.org/10.1186/s13195-022-00967-z