Cargando…

Evaluating statistical approaches to define clonal origin of tumours using bulk DNA sequencing: context is everything

Clonal analysis of tumour sequencing data enables the evaluation of the relationship of histologically distinct synchronous lesions, such as co-existing benign areas, and temporally distinct tumours, such as primary-recurrence comparisons. In this review, we summarise statistical approaches that are...

Descripción completa

Detalles Bibliográficos
Autores principales: Kader, Tanjina, Zethoven, Magnus, Gorringe, Kylie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809045/
https://www.ncbi.nlm.nih.gov/pubmed/35109903
http://dx.doi.org/10.1186/s13059-022-02600-6