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Evaluating statistical approaches to define clonal origin of tumours using bulk DNA sequencing: context is everything
Clonal analysis of tumour sequencing data enables the evaluation of the relationship of histologically distinct synchronous lesions, such as co-existing benign areas, and temporally distinct tumours, such as primary-recurrence comparisons. In this review, we summarise statistical approaches that are...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809045/ https://www.ncbi.nlm.nih.gov/pubmed/35109903 http://dx.doi.org/10.1186/s13059-022-02600-6 |