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Suppression of mitochondrial respiration by hydrogen sulfide in hibernating 13-lined ground squirrels

Hibernating mammals may suppress their basal metabolic rate during torpor by up to 95% to reduce energy expenditure during winter, but the underlying mechanisms remain poorly understood. Here we show that hydrogen sulfide (H(2)S), a ubiquitous signaling molecule, is a powerful inhibitor of respirati...

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Detalles Bibliográficos
Autores principales: Jensen, Birgitte S., Pardue, Sibile, Duffy, Brynne, Kevil, Christopher G., Staples, James F., Fago, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809085/
https://www.ncbi.nlm.nih.gov/pubmed/33887435
http://dx.doi.org/10.1016/j.freeradbiomed.2021.04.009