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Suppression of mitochondrial respiration by hydrogen sulfide in hibernating 13-lined ground squirrels
Hibernating mammals may suppress their basal metabolic rate during torpor by up to 95% to reduce energy expenditure during winter, but the underlying mechanisms remain poorly understood. Here we show that hydrogen sulfide (H(2)S), a ubiquitous signaling molecule, is a powerful inhibitor of respirati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809085/ https://www.ncbi.nlm.nih.gov/pubmed/33887435 http://dx.doi.org/10.1016/j.freeradbiomed.2021.04.009 |