Cargando…

Suppression of mitochondrial respiration by hydrogen sulfide in hibernating 13-lined ground squirrels

Hibernating mammals may suppress their basal metabolic rate during torpor by up to 95% to reduce energy expenditure during winter, but the underlying mechanisms remain poorly understood. Here we show that hydrogen sulfide (H(2)S), a ubiquitous signaling molecule, is a powerful inhibitor of respirati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jensen, Birgitte S., Pardue, Sibile, Duffy, Brynne, Kevil, Christopher G., Staples, James F., Fago, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809085/ https://www.ncbi.nlm.nih.gov/pubmed/33887435 http://dx.doi.org/10.1016/j.freeradbiomed.2021.04.009

Ejemplares similares

Hydrogen sulfide metabolism regulates endothelial solute barrier function
por: Yuan, Shuai, et al.
Publicado: (2016)

Assessment of Outer Retinal Remodeling in the Hibernating 13-Lined Ground Squirrel
por: Sajdak, Benjamin S., et al.
Publicado: (2018)

Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel
por: Grabek, Katharine R., et al.
Publicado: (2019)

Hydrogen sulfide stimulates xanthine oxidoreductase conversion to nitrite reductase and formation of NO
por: Pardue, Sibile, et al.
Publicado: (2020)

Suspension of Mitotic Activity in Dentate Gyrus of the Hibernating Ground Squirrel
por: Popov, Victor I., et al.
Publicado: (2011)

Impaired Skeletal Muscle Regeneration in the Absence of Fibrosis during Hibernation in 13-Lined Ground Squirrels
por: Andres-Mateos, Eva, et al.
Publicado: (2012)

Bile constituents in hibernating golden-mantled ground squirrels (Spermophilus lateralis)
por: Baker, Julie A, et al.
Publicado: (2009)

Cytoskeletal Regulation Dominates Temperature-Sensitive Proteomic Changes of Hibernation in Forebrain of 13-Lined Ground Squirrels
por: Hindle, Allyson G., et al.
Publicado: (2013)

Decreased availability of nitric oxide and hydrogen sulfide is a hallmark of COVID-19
por: Dominic, Paari, et al.
Publicado: (2021)

Regulation of Mitochondrial Respiration by Hydrogen Sulfide
por: Huang, Dandan, et al.
Publicado: (2023)

The effects of hibernation and forced disuse (neurectomy) on bone properties in arctic ground squirrels
por: Bogren, Lori K., et al.
Publicado: (2016)

Cytosolic phospholipase A2 regulation in the hibernating thirteen-lined ground squirrel
por: Woods, Ashley K., et al.
Publicado: (2007)

Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel
por: Chmura, Helen E., et al.
Publicado: (2022)

Expression Profiling and Structural Characterization of MicroRNAs in Adipose Tissues of Hibernating Ground Squirrels
por: Wu, Cheng-Wei, et al.
Publicado: (2014)

Extreme climate event promotes phenological mismatch between sexes in hibernating ground squirrels
por: Kucheravy, Caila E., et al.
Publicado: (2021)

Non-shivering thermogenesis is differentially regulated during the hibernation season in Arctic ground squirrels
por: Hunstiger, Moriah, et al.
Publicado: (2023)

Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias
por: Disbrow, Elizabeth, et al.
Publicado: (2021)

The heart of a hibernator: EGFR and MAPK signaling in cardiac muscle during the hibernation of thirteen-lined ground squirrels, Ictidomys tridecemlineatus
por: Childers, Christine L., et al.
Publicado: (2019)

Hydrogen Sulfide Stimulates Ischemic Vascular Remodeling Through Nitric Oxide Synthase and Nitrite Reduction Activity Regulating Hypoxia‐Inducible Factor‐1α and Vascular Endothelial Growth Factor–Dependent Angiogenesis
por: Bir, Shyamal C., et al.
Publicado: (2012)

Opposing Activity Changes in AMP Deaminase and AMP-Activated Protein Kinase in the Hibernating Ground Squirrel
por: Lanaspa, Miguel A., et al.
Publicado: (2015)

Remarkable Homeostasis of Protein Sialylation in Skeletal Muscles of Hibernating Daurian Ground Squirrels (Spermophilus dauricus)
por: Dang, Kai, et al.
Publicado: (2020)

Erythrocytes of Little Ground Squirrels Undergo Reversible Oxidative Stress During Arousal From Hibernation
por: Klichkhanov, Nisred K., et al.
Publicado: (2021)

Increased brain histamine H(3 )receptor expression during hibernation in golden-mantled ground squirrels
por: Sallmen, Tina, et al.
Publicado: (2003)

Up-regulation of Long Non-coding RNA TUG1 in Hibernating Thirteen-lined Ground Squirrels
por: Frigault, Jacques J., et al.
Publicado: (2016)

Pro-inflammatory AGE-RAGE signaling is activated during arousal from hibernation in ground squirrel adipose
por: Logan, Samantha M., et al.
Publicado: (2018)

Decreased bioavailability of hydrogen sulfide links vascular endothelium and atrial remodeling in atrial fibrillation
por: Watts, Megan, et al.
Publicado: (2020)

Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel, Ictidomys tridecemlineatus
por: Bell, Ryan A.V., et al.
Publicado: (2014)

Metabolic Hormone FGF21 Is Induced in Ground Squirrels during Hibernation but Its Overexpression Is Not Sufficient to Cause Torpor
por: Nelson, Bethany T., et al.
Publicado: (2013)

Transcriptional changes in muscle of hibernating arctic ground squirrels (Urocitellus parryii): implications for attenuation of disuse muscle atrophy
por: Goropashnaya, Anna V., et al.
Publicado: (2020)

Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels
por: Rice, Sarah A., et al.
Publicado: (2020)

Microbial gene expression during hibernation in arctic ground squirrels: greater differences across gut sections than in response to pre-hibernation dietary protein content
por: Grond, Kirsten, et al.
Publicado: (2023)

Methamphetamine causes cardiovascular dysfunction via cystathionine gamma lyase and hydrogen sulfide depletion
por: Kolluru, Gopi K., et al.
Publicado: (2022)

Characterization of Retinal Development in 13-Lined Ground Squirrels
por: Kandoi, Sangeetha, et al.
Publicado: (2022)

Weakened Contractile Performance and Mitochondrial Respiratory Complex Activity in Skeletal Muscle Improve during Interbout Arousal in Hibernating Daurian Ground Squirrel, Spermophilus dauricus
por: Wang, Huiping, et al.
Publicado: (2023)

Increased Na(+)/Ca(2+) Exchanger Activity Promotes Resistance to Excitotoxicity in Cortical Neurons of the Ground Squirrel (a Hibernator)
por: Zhao, Juan-Juan, et al.
Publicado: (2014)

Controllable oxidative stress and tissue specificity in major tissues during the torpor–arousal cycle in hibernating Daurian ground squirrels
por: Wei, Yanhong, et al.
Publicado: (2018)

Remarkable Plasticity of Bone Iron Homeostasis in Hibernating Daurian Ground Squirrels (Spermophilus dauricus) May Be Involved in Bone Maintenance
por: He, Yue, et al.
Publicado: (2022)

Self-Immolative Thiocarbamates Provide Access to Triggered H(2)S Donors and Analyte Replacement Fluorescent Probes
por: Steiger, Andrea K., et al.
Publicado: (2016)

Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels
por: Fu, Weiwei, et al.
Publicado: (2016)

The Raphe Pallidus and the Hypothalamic-Pituitary-Thyroid Axis Gate Seasonal Changes in Thermoregulation in the Hibernating Arctic Ground Squirrel (Urocitellus parryii)
por: Frare, Carla, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9pjacn6iv87h5jq6si6nnstjsv