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NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria

Silent information regulator factor 2-related enzyme 1 (Sirt1) is involved in the regulation of cell senescence, gene transcription, energy balance and oxidative stress. However, the effect of Sirt1 on atrial natriuretic factor (ANF) secretion, especially under hypoxic conditions is unclear. The pre...

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Detalles Bibliográficos
Autores principales: Li, Zhi-Yu, Liu, Ying, Wang, Yue-Ying, Li, Xiang, Han, Zhuo-Na, Hong, Lan, Li, Ying-Shun, Cui, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809118/
https://www.ncbi.nlm.nih.gov/pubmed/35029280
http://dx.doi.org/10.3892/mmr.2022.12600