Discovery of a novel nonsteroidal selective glucocorticoid receptor modulator by virtual screening and bioassays

Synthetic glucocorticoids (GCs) have been widely used in the treatment of a broad range of inflammatory diseases, but their clinic use is limited by undesired side effects such as metabolic disorders, osteoporosis, skin and muscle atrophies, mood disorders and hypothalamic-pituitary-adrenal (HPA) ax...

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Detalles Bibliográficos
Autores principales: Pang, Jin-ping, Hu, Xue-ping, Wang, Yun-xia, Liao, Jia-ning, Chai, Xin, Wang, Xu-wen, Shen, Chao, Wang, Jia-jia, Zhang, Lu-lu, Wang, Xin-yue, Zhu, Feng, Weng, Qin-jie, Xu, Lei, Hou, Ting-jun, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809242/
https://www.ncbi.nlm.nih.gov/pubmed/35110698
http://dx.doi.org/10.1038/s41401-021-00855-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809242/
https://www.ncbi.nlm.nih.gov/pubmed/35110698
http://dx.doi.org/10.1038/s41401-021-00855-6

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