Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

Methods to deliver gene editing agents in vivo as ribonucleoproteins could offer safety advantages over nucleic acid delivery approaches. We report the development and application of engineered DNA-free virus-like particles (eVLPs) that efficiently package and deliver base editor or Cas9 ribonucleop...

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Detalles Bibliográficos
Autores principales: Banskota, Samagya, Raguram, Aditya, Suh, Susie, Du, Samuel W., Davis, Jessie R., Choi, Elliot H., Wang, Xiao, Nielsen, Sarah C., Newby, Gregory A., Randolph, Peyton B., Osborn, Mark J., Musunuru, Kiran, Palczewski, Krzysztof, Liu, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809250/
https://www.ncbi.nlm.nih.gov/pubmed/35021064
http://dx.doi.org/10.1016/j.cell.2021.12.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809250/
https://www.ncbi.nlm.nih.gov/pubmed/35021064
http://dx.doi.org/10.1016/j.cell.2021.12.021

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