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FAdV-4 without Fiber-2 Is a Highly Attenuated and Protective Vaccine Candidate

Hepatitis-hydropericardium syndrome (HHS) caused by the highly pathogenic fowl adenovirus serotype 4 (FAdV-4) has resulted in huge economic losses to the poultry industry globally. The fiber-2 gene, as a major virulence determiner, is also an important vaccine target against FAdV-4. In this study, w...

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Detalles Bibliográficos
Autores principales: Xie, Quan, Wang, Weikang, Kan, Qiuqi, Mu, Yaru, Zhang, Wei, Chen, Jian, Li, Luyuan, Fu, Hui, Li, Tuofan, Wan, Zhimin, Gao, Wei, Shao, Hongxia, Qin, Aijian, Ye, Jianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809343/
https://www.ncbi.nlm.nih.gov/pubmed/35107364
http://dx.doi.org/10.1128/spectrum.01436-21