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Functional Analysis of the Expanded Phosphodiesterase Gene Family in Toxoplasma gondii Tachyzoites

Toxoplasma motility is both activated and suppressed by 3′,5′-cyclic nucleotide signaling. Cyclic GMP (cGMP) signaling through Toxoplasma gondii protein kinase G (TgPKG) activates motility, whereas cyclic AMP (cAMP) signaling through TgPKAc1 inhibits motility. Despite their importance, it remains un...

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Detalles Bibliográficos
Autores principales: Moss, William J., Patterson, Caitlyn E., Jochmans, Alexander K., Brown, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809380/
https://www.ncbi.nlm.nih.gov/pubmed/35107337
http://dx.doi.org/10.1128/msphere.00793-21