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An “OFF–ON–OFF” fluorescence protein-labeling probe for real-time visualization of the degradation of short-lived proteins in cellular systems

The ability to monitor proteolytic pathways that remove unwanted and damaged proteins from cells is essential for understanding the multiple processes used to maintain cellular homeostasis. In this study, we have developed a new protein-labeling probe that employs an ‘OFF–ON–OFF’ fluorescence switch...

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Detalles Bibliográficos
Autores principales: Reja, Shahi Imam, Hori, Yuichiro, Kamikawa, Takuya, Yamasaki, Kohei, Nishiura, Miyako, Bull, Steven D., Kikuchi, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809410/
https://www.ncbi.nlm.nih.gov/pubmed/35222926
http://dx.doi.org/10.1039/d1sc06274c