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Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade

Rhodium-catalyzed hydroacylation using alkynes substituted with pendant nucleophiles, delivers linear α,β-unsaturated enone intermediates with excellent regioselectivity. These adducts are used to construct a broad range of diversely substituted, saturated O-, N- and S-heterocycles in a one-pot proc...

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Detalles Bibliográficos
Autores principales: Iwumene, Ndidi U. N., Moseley, Daniel. F., Pullin, Robert D. C., Willis, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809418/
https://www.ncbi.nlm.nih.gov/pubmed/35222935
http://dx.doi.org/10.1039/d1sc06900d