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Fighting metallodrug resistance through alteration of drug metabolism and blockage of autophagic flux by mitochondria-targeting AIEgens

Metallodrug resistance has attracted a great deal of attention in cancer treatment. According to the cisplatin (cis-Pt) anticancer mechanism, a new strategy to overcome cis-Pt resistance through mitochondrial dysfunction is proposed. Two mitochondria-targeted aggregation-induced emission fluorogens...

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Detalles Bibliográficos
Autores principales: Su, Yan, Lin, Hai, Tu, Ying, Wang, Meng-Meng, Zhang, Guan-Dong, Yang, Jin, Liu, Hong-Ke, Su, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809423/
https://www.ncbi.nlm.nih.gov/pubmed/35222927
http://dx.doi.org/10.1039/d1sc06722b