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LncRNA TCONS_00145741 Knockdown Prevents Thrombin-Induced M1 Differentiation of Microglia in Intracerebral Hemorrhage by Enhancing the Interaction Between DUSP6 and JNK

Background: The differentiation of microglia from M1 to M2 exerts a pivotal role in the aggression of intracerebral hemorrhage (ICH), and long non-coding RNAs (lncRNAs) are associated with the differentiation of microglia. However, the underlying mechanism had not been fully clarified. Methods: The...

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Detalles Bibliográficos
Autores principales: Wu, Lanxiang, Zhan, Qingqing, Liu, Pan, Zheng, Heqing, Liu, Mingxu, Min, Jun, Xie, Liang, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809462/
https://www.ncbi.nlm.nih.gov/pubmed/35127692
http://dx.doi.org/10.3389/fcell.2021.684842