Pharmacological Inhibition of BACE1 Suppresses Glioblastoma Growth by Stimulating Macrophage Phagocytosis of Tumor Cells

Glioblastoma (GBM) contains abundant tumor-associated macrophages (TAMs). The majority of TAMs are tumor-promoting macrophages (pTAMs), while tumor-suppressive macrophages (sTAMs) are the minority. Thus, reprograming pTAMs into sTAMs represents an attractive therapeutic strategy. By screening a coll...

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Detalles Bibliográficos
Autores principales: Zhai, Kui, Huang, Zhi, Huang, Qian, Tao, Weiwei, Fang, Xiaoguang, Zhang, Aili, Li, Xiaoxia, Stark, George R., Hamilton, Thomas A., Bao, Shideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809483/
https://www.ncbi.nlm.nih.gov/pubmed/35122055
http://dx.doi.org/10.1038/s43018-021-00267-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809483/
https://www.ncbi.nlm.nih.gov/pubmed/35122055
http://dx.doi.org/10.1038/s43018-021-00267-9

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