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A noncanonical chaperone interacts with drug efflux pumps during their assembly into bacterial outer membranes
Bacteria have membrane-spanning efflux pumps to secrete toxic compounds ranging from heavy metal ions to organic chemicals, including antibiotic drugs. The overall architecture of these efflux pumps is highly conserved: with an inner membrane energy-transducing subunit coupled via an adaptor protein...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809574/ https://www.ncbi.nlm.nih.gov/pubmed/35061668 http://dx.doi.org/10.1371/journal.pbio.3001523 |