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Single-cell sequencing reveals lineage-specific dynamic genetic regulation of gene expression during human cardiomyocyte differentiation

Dynamic and temporally specific gene regulatory changes may underlie unexplained genetic associations with complex disease. During a dynamic process such as cellular differentiation, the overall cell type composition of a tissue (or an in vitro culture) and the gene regulatory profile of each cell c...

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Detalles Bibliográficos
Autores principales: Elorbany, Reem, Popp, Joshua M., Rhodes, Katherine, Strober, Benjamin J., Barr, Kenneth, Qi, Guanghao, Gilad, Yoav, Battle, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809621/
https://www.ncbi.nlm.nih.gov/pubmed/35061661
http://dx.doi.org/10.1371/journal.pgen.1009666