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A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB

The nuclear factor-kappa B (NF-κB) is a transcription factor with important roles in inflammation, immune response, and oncogenesis. Dysregulation of NF-κB signaling is associated with inflammation and certain cancers. We developed a gene expression biomarker predictive of NF-κB modulation and used...

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Detalles Bibliográficos
Autores principales: Korunes, Katharine L., Liu, Jie, Huang, Ruili, Xia, Menghang, Houck, Keith A., Corton, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809623/
https://www.ncbi.nlm.nih.gov/pubmed/35108274
http://dx.doi.org/10.1371/journal.pone.0261854