Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis

Dysregulation of calcium homeostasis has been hypothesized to play a role in Alzheimer’s disease (AD) pathogenesis. Increased calcium levels can impair axonal transport, disrupt synaptic transmission, and ultimately lead to cell death. Given the potential role of calcium dyshomeostasis in AD, there...

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Detalles Bibliográficos
Autores principales: Sadleir, Katherine R., Popovic, Jelena, Khatri, Ammaarah, Vassar, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809624/
https://www.ncbi.nlm.nih.gov/pubmed/35108319
http://dx.doi.org/10.1371/journal.pone.0263332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809624/
https://www.ncbi.nlm.nih.gov/pubmed/35108319
http://dx.doi.org/10.1371/journal.pone.0263332

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