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MRBLE-pep Measurements Reveal Accurate Binding Affinities for B56, a PP2A Regulatory Subunit

[Image: see text] Signal transduction pathways rely on dynamic interactions between protein globular domains and short linear motifs (SLiMs). The weak affinities of these interactions are essential to allow fast rewiring of signaling pathways and downstream responses but also pose technical challeng...

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Detalles Bibliográficos
Autores principales: Hein, Jamin B., Cyert, Martha S., Fordyce, Polly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809670/
https://www.ncbi.nlm.nih.gov/pubmed/35128539
http://dx.doi.org/10.1021/acsmeasuresciau.1c00008